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The transcription activator AtxA from Bacillus anthracis was employed for developing a tight-control, high-level, modulable and stationary-phase-specific transcription activity in Escherichia coli

The strong transcriptional activity of the virulent gene pagA in Bacillus anthracis has been proven to be anthrax toxin activator (AtxA)-regulated. However, the obscure pagA transcription mechanism hinders practical applications of this strong promoter. In this study, a 509-bp DNA fragment [termed 5...

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Detalles Bibliográficos
Autores principales: Liu, Ying-Xing, Zhuo, Xiao-Zhen, Li, Si-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424709/
https://www.ncbi.nlm.nih.gov/pubmed/36046151
http://dx.doi.org/10.1093/synbio/ysac014