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Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling

Purpose: The incidence of uric acid (UA)-induced kidney injury is increasing owing to the high incidence of hyperuricemia in recent years. The flower of Abelmoschus manihot (Linneus) Medik is a traditional Chinese medicinal herb widely used in the treatment of some kidney diseases. In our previous s...

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Detalles Bibliográficos
Autores principales: Ding, Zhihui, Zhao, Jing, Wang, Xufang, Li, Wei, Chen, Chong, Yong, Chen, Zhu, Yiye, Tian, Fang, Liu, Li, Yu, Manshu, Zhou, Enchao, Gu, Liubao, Yao, Chunlei, Gao, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424722/
https://www.ncbi.nlm.nih.gov/pubmed/36052125
http://dx.doi.org/10.3389/fphar.2022.907980