Cargando…

Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling

Purpose: The incidence of uric acid (UA)-induced kidney injury is increasing owing to the high incidence of hyperuricemia in recent years. The flower of Abelmoschus manihot (Linneus) Medik is a traditional Chinese medicinal herb widely used in the treatment of some kidney diseases. In our previous s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, Zhihui, Zhao, Jing, Wang, Xufang, Li, Wei, Chen, Chong, Yong, Chen, Zhu, Yiye, Tian, Fang, Liu, Li, Yu, Manshu, Zhou, Enchao, Gu, Liubao, Yao, Chunlei, Gao, Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424722/ https://www.ncbi.nlm.nih.gov/pubmed/36052125 http://dx.doi.org/10.3389/fphar.2022.907980

Ejemplares similares

TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis
por: Wu, Jingying, et al.
Publicado: (2023)

Total Extracts of Abelmoschus manihot L. Attenuates Adriamycin-Induced Renal Tubule Injury via Suppression of ROS-ERK1/2-Mediated NLRP3 Inflammasome Activation
por: Li, Wei, et al.
Publicado: (2019)

HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells
por: Yao, Feng, et al.
Publicado: (2022)

Blocking Caspase-1/Gsdmd and Caspase-3/-8/Gsdme pyroptotic pathways rescues silicosis in mice
por: Kang, Lulu, et al.
Publicado: (2022)

Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity
por: Shen, Xiujin, et al.
Publicado: (2021)

Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
por: Yu, Junhui, et al.
Publicado: (2019)

Chalcone Derivatives From Abelmoschus manihot Seeds Restrain NLRP3 Inflammasome Assembly by Inhibiting ASC Oligomerization
por: Su, Jinsong, et al.
Publicado: (2022)

The caspase-3/GSDME signal pathway as a switch between apoptosis and pyroptosis in cancer
por: Jiang, Mingxia, et al.
Publicado: (2020)

Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells
por: Yan, Liang, et al.
Publicado: (2021)

Antileukemic effect of venetoclax and hypomethylating agents via caspase-3/GSDME-mediated pyroptosis
por: Ye, Fanghua, et al.
Publicado: (2023)

PD-L1 Regulates Platelet Activation and Thrombosis via Caspase-3/GSDME Pathway
por: Li, Yulong, et al.
Publicado: (2022)

Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate
por: Hu, Lei, et al.
Publicado: (2020)

Caspase‐3‐mediated GSDME activation contributes to cisplatin‐ and doxorubicin‐induced secondary necrosis in mouse macrophages
por: Mai, Feng‐Yi, et al.
Publicado: (2019)

BECN1 modulates hematopoietic stem cells by targeting Caspase-3-GSDME-mediated pyroptosis
Publicado: (2022)

BECN1 modulates hematopoietic stem cells by targeting Caspase-3-GSDME-mediated pyroptosis
por: Yang, Xiuxiu, et al.
Publicado: (2020)

Total flavones of abelmoschus manihot enhances angiogenic ability both in vitro and in vivo
por: Tang, Lingyi, et al.
Publicado: (2017)

The pharmacological mechanism of Abelmoschus manihot in the treatment of chronic kidney disease
por: Wei, Cuiting, et al.
Publicado: (2023)

BIRC5 Inhibition Is Associated with Pyroptotic Cell Death via Caspase3-GSDME Pathway in Lung Adenocarcinoma Cells
por: Zhang, Qingwei, et al.
Publicado: (2023)

Nitidine chloride induces caspase 3/GSDME-dependent pyroptosis by inhibting PI3K/Akt pathway in lung cancer
por: Yu, Fei, et al.
Publicado: (2022)

Caspase‐3‐mediated GSDME induced Pyroptosis in breast cancer cells through the ROS/JNK signalling pathway
por: Zhang, Ziwen, et al.
Publicado: (2021)

Germacrone induces caspase-3/GSDME activation and enhances ROS production, causing HepG2 pyroptosis
por: Sun, Xinfeng, et al.
Publicado: (2022)

Myricetin activates the Caspase-3/GSDME pathway via ER stress induction of pyroptosis in lung cancer cells
por: Han, Jicheng, et al.
Publicado: (2022)

Total flavone of Abelmoschus Manihot improves colitis by promoting the growth of Akkermansia in mice
por: Bu, Fan, et al.
Publicado: (2021)

Cordyceps militaris extract induces apoptosis and pyroptosis via caspase‐3/PARP/GSDME pathways in A549 cell line
por: Hu, Zixuan, et al.
Publicado: (2021)

Abelmoschus manihot for Diabetic Nephropathy: A Systematic Review and Meta-Analysis
por: Shi, Liwei, et al.
Publicado: (2019)

Comparison of Multiple Bioactive Constituents in the Corolla and Other Parts of Abelmoschus manihot
por: Yin, Shengxin, et al.
Publicado: (2021)

Caspase-11 Interaction with NLRP3 Potentiates the Noncanonical Activation of the NLRP3 Inflammasome
por: Moretti, Julien, et al.
Publicado: (2022)

Osthole Induces Apoptosis and Caspase-3/GSDME-Dependent Pyroptosis via NQO1-Mediated ROS Generation in HeLa Cells
por: Wang, Juan, et al.
Publicado: (2022)

Liproxstatin-1 induces cell cycle arrest, apoptosis, and caspase-3/GSDME-dependent secondary pyroptosis in K562 cells
por: Dong, Hai-Qun, et al.
Publicado: (2022)

Protective Effect of the Abelmoschus manihot Flower Extract on DSS-Induced Ulcerative Colitis in Mice
por: Wu, Bensheng, et al.
Publicado: (2021)

Gastroprotective Activity of the Total Flavones from Abelmoschus manihot (L.) Medic Flowers
por: Zhang, Jun, et al.
Publicado: (2020)

Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections
por: Zheng, Min, et al.
Publicado: (2021)

Effects of Abelmoschus manihot Flower Extract on Enhancing Sexual Arousal and Reproductive Performance in Zebrafish
por: Chang, Chi-Chang, et al.
Publicado: (2022)

Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival
por: Pu, Xuan, et al.
Publicado: (2016)

The role of caspase-1, caspase-4 and NLRP3 in regulating the host cell response evoked by uropathogenic Escherichia coli
por: Lindblad, Anna, et al.
Publicado: (2022)

GSDME-Dependent Incomplete Pyroptosis Permits Selective IL-1α Release under Caspase-1 Inhibition
por: Aizawa, Emi, et al.
Publicado: (2020)

Supplementation of Abelmoschus manihot Ameliorates Diabetic Nephropathy and Hepatic Steatosis by Activating Autophagy in Mice
por: Kim, Hwajin, et al.
Publicado: (2018)

Therapeutic Effect of Abelmoschus manihot on Type 2 Diabetic Nonproliferative Retinopathy and the Involvement of VEGF
por: Zhao, Yue, et al.
Publicado: (2020)

Integrated Network Pharmacology Analysis and Pharmacological Evaluation to Explore the Active Components and Mechanism of Abelmoschus manihot (L.) Medik. on Renal Fibrosis
por: Gu, Lifei, et al.
Publicado: (2020)

Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells
por: An, Haein, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ntf2km93ad0obd1vjn9ojlnq0h