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Anti-PD-L1 immunoconjugates for cancer therapy: Are available antibodies good carriers for toxic payload delivering?

Immune checkpoint mechanisms are important molecular cell systems that maintain tolerance toward autoantigens in order to prevent immunity-mediated accidental damage. It is well known that cancer cells may exploit these molecular and cellular mechanisms to escape recognition and elimination by immun...

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Detalles Bibliográficos
Autores principales: Zanello, Andrea, Bortolotti, Massimo, Maiello, Stefania, Bolognesi, Andrea, Polito, Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424723/
https://www.ncbi.nlm.nih.gov/pubmed/36052121
http://dx.doi.org/10.3389/fphar.2022.972046