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Disruption of the VAPB-PTPIP51 ER-mitochondria tethering proteins in post-mortem human amyotrophic lateral sclerosis

Signaling between the endoplasmic reticulum (ER) and mitochondria regulates many neuronal functions that are perturbed in amyotrophic lateral sclerosis (ALS) and perturbation to ER-mitochondria signaling is seen in cell and transgenic models of ALS. However, there is currently little evidence that E...

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Detalles Bibliográficos
Autores principales: Hartopp, Naomi, Lau, Dawn H W., Martin-Guerrero, Sandra M., Markovinovic, Andrea, Mórotz, Gábor M., Greig, Jenny, Glennon, Elizabeth B., Troakes, Claire, Gomez-Suaga, Patricia, Noble, Wendy, Miller, Christopher C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424765/
https://www.ncbi.nlm.nih.gov/pubmed/36051435
http://dx.doi.org/10.3389/fcell.2022.950767