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Of problems and opportunities—How to treat and how to not treat crystallographic fragment screening data

In their recent commentary in Protein Science, Jaskolski et al. analyzed three randomly picked diffraction data sets from fragment‐screening group depositions from the PDB and, based on that, they claimed that such data are principally problematic. We demonstrate here that if such data are treated p...

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Detalles Bibliográficos
Autores principales: Weiss, Manfred S., Wollenhaupt, Jan, Correy, Galen J., Fraser, James S., Heine, Andreas, Klebe, Gerhard, Krojer, Tobias, Thunissen, Marjolein, Pearce, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424839/
https://www.ncbi.nlm.nih.gov/pubmed/36040268
http://dx.doi.org/10.1002/pro.4391