Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma

Glioblastoma (GBM) is a high-grade, aggressive brain tumor with dismal median survival time of 15 months. Chromosome 6q (Ch6q) is a hotspot of genomic alterations, which is commonly deleted or hyper-methylated in GBM. Two neighboring genes in this region, QKI and PRKN have been appointed as tumor su...

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Detalles Bibliográficos
Autores principales: Aksoy Yasar, Fatma Betul, Shingu, Takashi, Zamler, Daniel B., Zaman, Mohammad Fayyad, Chien, Derek Lin, Zhang, Qiang, Ren, Jiangong, Hu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424994/
https://www.ncbi.nlm.nih.gov/pubmed/36051438
http://dx.doi.org/10.3389/fcell.2022.931387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424994/
https://www.ncbi.nlm.nih.gov/pubmed/36051438
http://dx.doi.org/10.3389/fcell.2022.931387

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