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Secretagogin is a Ca(2+)-dependent stress-responsive chaperone that may also play a role in aggregation-based proteinopathies

Secretagogin (SCGN) is a three-domain hexa-EF-hand Ca(2+)-binding protein that plays a regulatory role in the release of several hormones. SCGN is expressed largely in pancreatic β-cells, certain parts of the brain, and also in neuroendocrine tissues. The expression of SCGN is altered in several dis...

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Detalles Bibliográficos
Autores principales: Chidananda, Amrutha H., Khandelwal, Radhika, Jamkhindikar, Aditya, Pawar, Asmita D., Sharma, Anand K., Sharma, Yogendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425029/
https://www.ncbi.nlm.nih.gov/pubmed/35870554
http://dx.doi.org/10.1016/j.jbc.2022.102285