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Secretagogin is a Ca(2+)-dependent stress-responsive chaperone that may also play a role in aggregation-based proteinopathies
Secretagogin (SCGN) is a three-domain hexa-EF-hand Ca(2+)-binding protein that plays a regulatory role in the release of several hormones. SCGN is expressed largely in pancreatic β-cells, certain parts of the brain, and also in neuroendocrine tissues. The expression of SCGN is altered in several dis...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425029/ https://www.ncbi.nlm.nih.gov/pubmed/35870554 http://dx.doi.org/10.1016/j.jbc.2022.102285 |