Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2

BACKGROUND & AIMS: More than half of Crohn’s disease patients develop intestinal fibrosis-induced intestinal strictures. Elafin is a human protease inhibitor that is down-regulated in the stricturing intestine of Crohn’s disease patients. We investigated the efficacy of elafin in reversing intes...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Ying, Fontenot, Lindsey, Chupina Estrada, Andrea, Nelson, Becca, Wang, Jiani, Shih, David Q., Ho, Wendy, Mattai, S. Anjani, Rieder, Florian, Jensen, Dane D., Bunnett, Nigel W., Koon, Hon Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425040/
https://www.ncbi.nlm.nih.gov/pubmed/35840034
http://dx.doi.org/10.1016/j.jcmgh.2022.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425040/
https://www.ncbi.nlm.nih.gov/pubmed/35840034
http://dx.doi.org/10.1016/j.jcmgh.2022.06.011

Ejemplares similares