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Lynch syndrome pre-screening and comprehensive characterization in a multi-center large cohort of Chinese patients with colorectal cancer

OBJECTIVE: Lynch syndrome (LS) pre-screening methods remain under-investigated in colorectal cancers (CRCs) in Asia. Here, we aimed to systematically investigate LS pre-screening and comprehensively characterize LS CRCs. METHODS: Microsatellite instability (MSI) and germline variants of DNA mismatch...

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Detalles Bibliográficos
Autores principales: Li, Yan, Fan, Lihong, Zheng, Jianming, Nie, Xiu, Sun, Yu, Feng, Qin, Lian, Shenyi, Bai, Wenqi, Cai, Weijing, Yang, Yanan, Su, Bo, Xi, Yanfeng, Lin, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425183/
https://www.ncbi.nlm.nih.gov/pubmed/35638907
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0585