Antiplatelet antibody predicts platelet desialylation and apoptosis in immune thrombocytopenia

Immune thrombocytopenia (ITP) is a bleeding disorder caused by dysregulated B- and T- cell functions, which lead to platelet destruction. A well-recognized mechanism of ITP pathogenesis involves anti-platelet and anti-megakaryocyte antibodies recognizing membrane glycoprotein (GP) complexes, mainly...

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Detalles Bibliográficos
Autores principales: Zheng, Shiying Silvia, Ahmadi, Zohra, Leung, Halina Hoi Laam, Wong, Rose, Yan, Feng, Perdomo, José Sail, Chong, Beng Hock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Platelet Biology & its Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425302/
https://www.ncbi.nlm.nih.gov/pubmed/35199503
http://dx.doi.org/10.3324/haematol.2021.279751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425302/
https://www.ncbi.nlm.nih.gov/pubmed/35199503
http://dx.doi.org/10.3324/haematol.2021.279751

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