Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets

The multidrug resistance protein 4 (MRP4) is highly expressed in platelets and several lines of evidence point to an impact on platelet function. MRP4 represents a transporter for cyclic nucleotides as well as for certain lipid mediators. The aim of the present study was to comprehensively character...

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Detalles Bibliográficos
Autores principales: Wolf, Robert, Grammbauer, Sophie, Palankar, Raghavendra, Tolksdorf, Céline, Moritz, Eileen, Böhm, Andreas, Hasan, Mahmoud, Hafkemeyer, Annika, Greinacher, Andreas, Tzvetkov, Mladen V., Rauch, Bernhard H., Jedlitschky, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Platelet Biology & its Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425312/
https://www.ncbi.nlm.nih.gov/pubmed/35295075
http://dx.doi.org/10.3324/haematol.2021.279761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425312/
https://www.ncbi.nlm.nih.gov/pubmed/35295075
http://dx.doi.org/10.3324/haematol.2021.279761

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