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High tumor burden before blinatumomab has a negative impact on the outcome of adult patients with B-cell precursor acute lymphoblastic leukemia. A real-world study by the GRAALL

Blinatumomab is a bispecific T-cell engager approved for B-cell precursor acute lymphoblastic leukemia (B-ALL) with persistent minimal residual disease (MRD) or in relapse. The prognostic impact of tumor load has been suggested before other immunotherapies but remains poorly explored before blinatum...

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Detalles Bibliográficos
Autores principales: Cabannes-Hamy, Aurélie, Brissot, Eolia, Leguay, Thibaut, Huguet, Françoise, Chevallier, Patrice, Hunault, Mathilde, Escoffre-Barbe, Martine, Cluzeau, Thomas, Balsat, Marie, Nguyen, Stéphanie, Pasquier, Florence, Alexis, Magda, Lhéritier, Véronique, Pastoret, Cédric, Delabesse, Eric, Clappier, Emmanuelle, Dombret, Hervé, Boissel, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425331/
https://www.ncbi.nlm.nih.gov/pubmed/35263986
http://dx.doi.org/10.3324/haematol.2021.280078