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High tumor burden before blinatumomab has a negative impact on the outcome of adult patients with B-cell precursor acute lymphoblastic leukemia. A real-world study by the GRAALL
Blinatumomab is a bispecific T-cell engager approved for B-cell precursor acute lymphoblastic leukemia (B-ALL) with persistent minimal residual disease (MRD) or in relapse. The prognostic impact of tumor load has been suggested before other immunotherapies but remains poorly explored before blinatum...
Autores principales: | Cabannes-Hamy, Aurélie, Brissot, Eolia, Leguay, Thibaut, Huguet, Françoise, Chevallier, Patrice, Hunault, Mathilde, Escoffre-Barbe, Martine, Cluzeau, Thomas, Balsat, Marie, Nguyen, Stéphanie, Pasquier, Florence, Alexis, Magda, Lhéritier, Véronique, Pastoret, Cédric, Delabesse, Eric, Clappier, Emmanuelle, Dombret, Hervé, Boissel, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425331/ https://www.ncbi.nlm.nih.gov/pubmed/35263986 http://dx.doi.org/10.3324/haematol.2021.280078 |
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