Genetic and genomic analysis of acute lymphoblastic leukemia in older adults reveals a distinct profile of abnormalities: analysis of 210 patients from the UKALL14 and UKALL60+ clinical trials

Despite being predominantly a childhood disease, the incidence of acute lymphoblastic leukemia (ALL) has a second peak in adults aged 60 years and over. These older adults fare extremely poorly with existing treatment strategies and very few studies have undertaken a comprehensive genetic and genomi...

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Detalles Bibliográficos
Autores principales: Creasey, Thomas, Barretta, Emilio, Ryan, Sarra L., Butler, Ellie, Kirkwood, Amy A., Leongamornlert, Daniel, Papaemmanuil, Elli, Patrick, Pip, Clifton-Hadley, Laura, Patel, Bela, Menne, Tobias, McMillan, Andrew K., Harrison, Christine J., Rowntree, Clare J., Morley, Nick, Marks, David I., Fielding, Adele K., Moorman, Anthony V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Article - Acute Lymphoblastic Leukemia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425332/
https://www.ncbi.nlm.nih.gov/pubmed/34788984
http://dx.doi.org/10.3324/haematol.2021.279177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425332/
https://www.ncbi.nlm.nih.gov/pubmed/34788984
http://dx.doi.org/10.3324/haematol.2021.279177

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