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Activation of Transient Receptor Potential Vanilloid-3 Channels in Keratinocytes Induces Pruritus in Humans

Carvacrol, a natural transient receptor potential vanilloid-3 activator, has been reported to cause pruritus in mice. This study aimed to evaluate the effects of carvacrol and various antipruritic agents in humans. A stimulation test with carvacrol, β-alanine, and histamine was performed. After appl...

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Detalles Bibliográficos
Autores principales: KIM, Jin Cheol, KIM, Han Bi, SHIM, Won-Sik, KWAK, In Suk, CHUNG, Bo Young, KANG, Seok Young, PARK, Chun Wook, KIM, Hye One
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Publication of Acta Dermato-Venereologica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425626/
https://www.ncbi.nlm.nih.gov/pubmed/34184069
http://dx.doi.org/10.2340/00015555-3855