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A Pitx3-deficient developmental mouse model for fine motor, olfactory, and gastrointestinal symptoms of Parkinson’s disease

Parkinson’s disease (PD) is characterized by the selective death of substantia nigra pars compacta (SNpc) dopaminergic neurons and includes both motor and non-motor symptoms. While numerous models exist for the study of typical PD motor deficits, fewer exist for non-motor symptoms. Previous studies...

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Detalles Bibliográficos
Autores principales: Song, Bin, Feldmann, Jacob W., Cao, Shibo, Feitosa, Melissa, Kong, Youngbin, Kim, Woori, Schweitzer, Altana, Leblanc, Pierre, Schweitzer, Jeffrey S., Kim, Kwang-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425627/
https://www.ncbi.nlm.nih.gov/pubmed/35636646
http://dx.doi.org/10.1016/j.nbd.2022.105777