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A genetic model for central chondrosarcoma evolution correlates with patient outcome

BACKGROUND: Central conventional chondrosarcoma (CS) is the most common subtype of primary malignant bone tumour in adults. Treatment options are usually limited to surgery, and prognosis is challenging. These tumours are characterised by the presence and absence of IDH1 and IDH2 mutations, and rece...

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Detalles Bibliográficos
Autores principales: Cross, William, Lyskjær, Iben, Lesluyes, Tom, Hargreaves, Steven, Strobl, Anna-Christina, Davies, Christopher, Waise, Sara, Hames-Fathi, Shadi, Oukrif, Dahmane, Ye, Hongtao, Amary, Fernanda, Tirabosco, Roberto, Gerrand, Craig, Baker, Toby, Barnes, David, Steele, Christopher, Alexandrov, Ludmil, Bond, Gareth, Cool, Paul, Pillay, Nischalan, Loo, Peter Van, Flanagan, Adrienne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426036/
https://www.ncbi.nlm.nih.gov/pubmed/36042521
http://dx.doi.org/10.1186/s13073-022-01084-0