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Sappanone a prevents diabetic kidney disease by inhibiting kidney inflammation and fibrosis via the NF-κB signaling pathway

Background: Low grade of sterile inflammation plays detrimental roles in the progression of diabetic kidney disease (DKD). Sappanone A (SA), a kind of homoisoflavanone isolated from the heartwood of Caesalpinia sappan, exerts anti-inflammatory effects in acute kidney injury. However, whether SA has...

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Detalles Bibliográficos
Autores principales: Wang, Zhe, Chen, Zhida, Wang, Xinyi, Hu, Yepeng, Kong, Jing, Lai, Jiabin, Li, Tiekun, Hu, Bibi, Zhang, Yikai, Zheng, Xianan, Liu, Xiaoxian, Wang, Shengyao, Ye, Shu, Zhou, Qiao, Zheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426375/
https://www.ncbi.nlm.nih.gov/pubmed/36052141
http://dx.doi.org/10.3389/fphar.2022.953004