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Mas‐related G protein‐coupled receptor type D antagonism improves portal hypertension in cirrhotic rats

Splanchnic vasodilatation contributes to the development and aggravation of portal hypertension (PHT). We previously demonstrated that in cirrhosis, angiotensin‐ mediates splanchnic vasodilatation through the Mas receptor (MasR). In this study, we investigated whether the recently characterized seco...

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Detalles Bibliográficos
Autores principales: Gunarathne, Lakmie S., Rajapaksha, Indu G., Casey, Stephen, Qaradakhi, Tawar, Zulli, Anthony, Rajapaksha, Harinda, Trebicka, Jonel, Angus, Peter W., Herath, Chandana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426402/
https://www.ncbi.nlm.nih.gov/pubmed/35593203
http://dx.doi.org/10.1002/hep4.1987