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Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis

Liver fibrosis and cirrhosis have limited therapeutic options and represent a serious unmet patient need. Recent use of single‐cell RNA sequencing (scRNAseq) has identified enriched cell types infiltrating cirrhotic livers but without defining the microanatomical location of these lineages thoroughl...

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Detalles Bibliográficos
Autores principales: Chung, Brian K., Øgaard, Jonas, Reims, Henrik Mikael, Karlsen, Tom H., Melum, Espen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426406/
https://www.ncbi.nlm.nih.gov/pubmed/35726350
http://dx.doi.org/10.1002/hep4.2001