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Granulocyte colony‐stimulating factor attenuates liver damage by M2 macrophage polarization and hepatocyte proliferation in alcoholic hepatitis in mice

Massive inflammation and liver failure are main contributors to the high mortality in alcohol‐associated hepatitis (AH). In recent clinical trials, granulocyte colony‐stimulating factor (G‐CSF) therapy improved liver function and survival in patients with AH. However, the mechanisms of G‐CSF‐mediate...

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Detalles Bibliográficos
Autores principales: Cho, Yeonhee, Joshi, Radhika, Lowe, Patrick, Copeland, Christopher, Ribeiro, Marcelle, Morel, Caroline, Catalano, Donna, Szabo, Gyongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426408/
https://www.ncbi.nlm.nih.gov/pubmed/35997009
http://dx.doi.org/10.1002/hep4.1925