Human Nasal Organoids Model SARS-CoV-2 Upper Respiratory Infection and Recapitulate the Differential Infectivity of Emerging Variants

The human upper respiratory tract, specifically the nasopharyngeal epithelium, is the entry portal and primary infection site of respiratory viruses. Productive infection of SARS-CoV-2 in the nasal epithelium constitutes the cellular basis of viral pathogenesis and transmissibility. Yet a robust and...

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Detalles Bibliográficos
Autores principales: Chiu, Man Chun, Li, Cun, Liu, Xiaojuan, Song, Wenjun, Wan, Zhixin, Yu, Yifei, Huang, Jingjing, Xiao, Ding, Chu, Hin, Cai, Jian-Piao, To, Kelvin Kai-Wang, Yuen, Kwok Yung, Zhou, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426414/
https://www.ncbi.nlm.nih.gov/pubmed/35938726
http://dx.doi.org/10.1128/mbio.01944-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426414/
https://www.ncbi.nlm.nih.gov/pubmed/35938726
http://dx.doi.org/10.1128/mbio.01944-22

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