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Indole Sensing Regulator (IsrR) Promotes Virulence Gene Expression in Enteric Pathogens

Enteric pathogens such as enterohemorrhagic E. coli (EHEC) and its surrogate murine model Citrobacter rodentium sense indole levels within the gut to navigate its biogeography and modulate virulence gene expression. Indole is a microbiota-derived signal that is more abundant in the intestinal lumen,...

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Detalles Bibliográficos
Autores principales: Kumar, Aman, Russell, Regan M., Hoskan, Mehmet Ali, Sperandio, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426417/
https://www.ncbi.nlm.nih.gov/pubmed/35916401
http://dx.doi.org/10.1128/mbio.01939-22