Genistein Targets STING-Driven Antiviral Responses

Cytoplasmic detection of DNA by cyclic GMP-AMP (cGAMP) synthase (cGAS) is an essential component of antiviral responses. Upon synthesis, cGAMP binds to the stimulator of interferon (IFN) genes (STING) in infected and adjacent cells through intercellular transfer by connexins forming gap-junctions, e...

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Detalles Bibliográficos
Autores principales: Ullah, Tomalika R., Balka, Katherine R., Ambrose, Rebecca L., Pépin, Geneviève, Wilce, Matthew C. J., Wilce, Jacqueline A., Thomas, Belinda J., De Nardo, Dominic, Williams, Bryan R. G., Gantier, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426420/
https://www.ncbi.nlm.nih.gov/pubmed/35924852
http://dx.doi.org/10.1128/mbio.02064-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426420/
https://www.ncbi.nlm.nih.gov/pubmed/35924852
http://dx.doi.org/10.1128/mbio.02064-22

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