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The Akt Forkhead Box O Transcription Factor Axis Regulates Human Cytomegalovirus Replication
The protein kinase Akt broadly impacts many cellular processes, including mRNA translation, metabolism, apoptosis, and stress responses. Inhibition of phosphatidylinositol 3-kinase (PI3K), a lipid kinase pivotal to Akt activation, triggers various herpesviruses to reactivate from latency. Hence, dec...
Autores principales: | Zhang, Hongbo, Domma, Anthony J., Goodrum, Felicia D., Moorman, Nathaniel J., Kamil, Jeremy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426471/ https://www.ncbi.nlm.nih.gov/pubmed/35946797 http://dx.doi.org/10.1128/mbio.01042-22 |
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