Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs P-Glycoprotein Expression

P-glycoprotein (P-gp) is a key component of the intestinal epithelium playing a pivotal role in removal of toxins and efflux of endocannabinoids to prevent excessive inflammation and sustain homeostasis. Recent studies revealed butyrate and secondary bile acids, produced by the intestinal microbiome...

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Detalles Bibliográficos
Autores principales: Foley, Sage E., Dente, Michael J., Lei, Xuqiu, Sallis, Benjamin F., Loew, Ethan B., Meza-Segura, Mario, Fitzgerald, Katherine A., McCormick, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426490/
https://www.ncbi.nlm.nih.gov/pubmed/35968955
http://dx.doi.org/10.1128/mbio.01993-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426490/
https://www.ncbi.nlm.nih.gov/pubmed/35968955
http://dx.doi.org/10.1128/mbio.01993-22

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