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The Specificity of ParR Binding Determines the Incompatibility of Conjugative Plasmids in Clostridium perfringens

Plasmids that encode the same replication machinery are generally unable to coexist in the same bacterial cell. However, Clostridium perfringens strains often carry multiple conjugative toxin or antibiotic resistance plasmids that are closely related and encode similar Rep proteins. In many bacteria...

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Detalles Bibliográficos
Autores principales: Watts, Thomas D., Traore, Daouda A. K., Atkinson, Sarah C., Lao, Carmen, Caltabiano, Natalie, Rood, Julian I., Adams, Vicki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426499/
https://www.ncbi.nlm.nih.gov/pubmed/35726914
http://dx.doi.org/10.1128/mbio.01356-22