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CDC50 Orthologues in Plasmodium falciparum Have Distinct Roles in Merozoite Egress and Trophozoite Maturation

In model organisms, type IV ATPases (P4-ATPases) require cell division control protein 50 (CDC50) chaperones for their phospholipid flipping activity. In the malaria parasite Plasmodium falciparum, guanylyl cyclase alpha (GCα) is an integral membrane protein that is essential for release (egress) of...

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Detalles Bibliográficos
Autores principales: Patel, Avnish, Nofal, Stephanie D., Blackman, Michael J., Baker, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426505/
https://www.ncbi.nlm.nih.gov/pubmed/35862778
http://dx.doi.org/10.1128/mbio.01635-22