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Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium

Influenza A virus (IAV) causes significant morbidity and mortality in the human population. Tethered mucin 1 (MUC1) is highly expressed in airway epithelium, the primary site of IAV replication, and also by other cell types that influence IAV infection, including macrophages. MUC1 has the potential...

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Detalles Bibliográficos
Autores principales: Iverson, Ethan, Griswold, Kira, Song, Daniel, Gagliardi, Talita B., Hamidzadeh, Kajal, Kesimer, Mehmet, Sinha, Sanju, Perry, Melissa, Duncan, Gregg A., Scull, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426523/
https://www.ncbi.nlm.nih.gov/pubmed/35699372
http://dx.doi.org/10.1128/mbio.01055-22