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Enzymatic Specificity of Conserved Rho GTPase Deamidases Promotes Invasion of Vibrio parahaemolyticus at the Expense of Infection

Vibrio parahaemolyticus is among the leading causes of bacterial seafood-borne acute gastroenteritis. Like many intracellular pathogens, V. parahaemolyticus invades host cells during infection by deamidating host small Rho GTPases. The Rho GTPase deamidating activity of VopC, a type 3 secretion syst...

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Detalles Bibliográficos
Autores principales: Lafrance, Alexander E., Chimalapati, Suneeta, Garcia Rodriguez, Nalleli, Kinch, Lisa N., Kaval, Karan Gautam, Orth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426531/
https://www.ncbi.nlm.nih.gov/pubmed/35862776
http://dx.doi.org/10.1128/mbio.01629-22