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Genomic Diversity across Candida auris Clinical Isolates Shapes Rapid Development of Antifungal Resistance In Vitro and In Vivo

Antifungal drug resistance and tolerance pose a serious threat to global public health. In the human fungal pathogen, Candida auris, resistance to triazole, polyene, and echinocandin antifungals is rising, resulting in multidrug resistant isolates. Here, we use genome analysis and in vitro evolution...

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Detalles Bibliográficos
Autores principales: Burrack, Laura S., Todd, Robert T., Soisangwan, Natthapon, Wiederhold, Nathan P., Selmecki, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426540/
https://www.ncbi.nlm.nih.gov/pubmed/35862787
http://dx.doi.org/10.1128/mbio.00842-22