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Gene Coexpression Connectivity Predicts Gene Targets Underlying High Ionic-Liquid Tolerance in Yarrowia lipolytica

Microbial tolerance to organic solvents such as ionic liquids (ILs) is a robust phenotype beneficial for novel biotransformation. While most microbes become inhibited in 1% to 5% (vol/vol) IL (e.g., 1-ethyl-3-methylimidazolium acetate), we engineered a robust Yarrowia lipolytica strain (YlCW001) tha...

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Detalles Bibliográficos
Autores principales: Walker, Caleb, Ryu, Seunghyun, Garcia, Sergio, Dooley, David, Mendoza, Brian, Trinh, Cong T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426553/
https://www.ncbi.nlm.nih.gov/pubmed/35862814
http://dx.doi.org/10.1128/msystems.00348-22