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A Multitrait Locus Regulates Sarbecovirus Pathogenesis

Infectious diseases have shaped the human population genetic structure, and genetic variation influences the susceptibility to many viral diseases. However, a variety of challenges have made the implementation of traditional human Genome-wide Association Studies (GWAS) approaches to study these infe...

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Detalles Bibliográficos
Autores principales: Schäfer, Alexandra, Leist, Sarah R., Gralinski, Lisa E., Martinez, David R., Winkler, Emma S., Okuda, Kenichi, Hawkins, Padraig E., Gully, Kendra L., Graham, Rachel L., Scobey, D. Trevor, Bell, Timothy A., Hock, Pablo, Shaw, Ginger D., Loome, Jennifer F., Madden, Emily A., Anderson, Elizabeth, Baxter, Victoria K., Taft-Benz, Sharon A., Zweigart, Mark R., May, Samantha R., Dong, Stephanie, Clark, Matthew, Miller, Darla R., Lynch, Rachel M., Heise, Mark T., Tisch, Roland, Boucher, Richard C., Pardo Manuel de Villena, Fernando, Montgomery, Stephanie A., Diamond, Michael S., Ferris, Martin T., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426612/
https://www.ncbi.nlm.nih.gov/pubmed/35862771
http://dx.doi.org/10.1128/mbio.01454-22