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LNA oligonucleotide mediates an anti‐inflammatory effect in autoimmune myocarditis via targeting lactate dehydrogenase B

Treatment of myocarditis is often limited to symptomatic treatment due to unknown pathomechanisms. In order to identify new therapeutic approaches, the contribution of locked nucleic acid antisense oligonucleotides (LNA ASOs) in autoimmune myocarditis was investigated. Hence, A/J mice were immunized...

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Detalles Bibliográficos
Autores principales: Bockstahler, Mariella, Salbach, Christian, Müller, Anna‐Maria, Kübler, Andrea, Müller, Oliver J., Katus, Hugo A., Frey, Norbert, Kaya, Ziya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426621/
https://www.ncbi.nlm.nih.gov/pubmed/34606637
http://dx.doi.org/10.1111/imm.13421