CDK4: a master regulator of the cell cycle and its role in cancer

The cell cycle is regulated in part by cyclins and their associated serine/threonine cyclin-dependent kinases, or CDKs. CDK4, in conjunction with the D-type cyclins, mediates progression through the G(1) phase when the cell prepares to initiate DNA synthesis. Although Cdk4-null mutant mice are viabl...

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Detalles Bibliográficos
Autores principales: Baker, Stacey J., Poulikakos, Poulikos I., Irie, Hanna Y., Parekh, Samir, Reddy, E. Premkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426627/
https://www.ncbi.nlm.nih.gov/pubmed/36051751
http://dx.doi.org/10.18632/genesandcancer.221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426627/
https://www.ncbi.nlm.nih.gov/pubmed/36051751
http://dx.doi.org/10.18632/genesandcancer.221

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