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Persistent expression of activation markers on Mycobacterium tuberculosis-specific CD4 T cells in smear negative TB patients

BACKGROUND: T cell activation (HLA-DR, CD-38), proliferation (KI-67), and functional (IFN-γ, TNF-α) markers have recently been shown to be useful in predicting and monitoring anti-TB responses in smear positive TB, but previous research did not characterize the activation and proliferation profiles...

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Detalles Bibliográficos
Autores principales: Esmael, Ahmed, Mihret, Adane, Abebe, Tamrat, Mussa, Daniel, Neway, Sebsibe, Ernst, Joel, Rengarajan, Jyothi, Wassie, Liya, Howe, Rawleigh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426896/
https://www.ncbi.nlm.nih.gov/pubmed/36040958
http://dx.doi.org/10.1371/journal.pone.0271234