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Genome-wide analysis of Schistosoma mansoni reveals limited population structure and possible praziquantel drug selection pressure within Ugandan hot-spot communities

Populations within schistosomiasis control areas, especially those in Africa, are recommended to receive regular mass drug administration (MDA) with praziquantel (PZQ) as the main strategy for controlling the disease. The impact of PZQ treatment on schistosome genetics remains poorly understood, and...

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Detalles Bibliográficos
Autores principales: Vianney, Tushabe John, Berger, Duncan J., Doyle, Stephen R., Sankaranarayanan, Geetha, Serubanja, Joel, Nakawungu, Prossy Kabuubi, Besigye, Fred, Sanya, Richard E., Holroyd, Nancy, Allan, Fiona, Webb, Emily L., Elliott, Alison M., Berriman, Matthew, Cotton, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426917/
https://www.ncbi.nlm.nih.gov/pubmed/35981002
http://dx.doi.org/10.1371/journal.pntd.0010188