Discovery of positive and purifying selection in metagenomic time series of hypermutator microbial populations

A general method to infer both positive and purifying selection during the real-time evolution of hypermutator pathogens would be broadly useful. To this end, we introduce a Simple Test to Infer Mode of Selection (STIMS) from metagenomic time series of evolving microbial populations. We test STIMS o...

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Detalles Bibliográficos
Autores principales: Maddamsetti, Rohan, Grant, Nkrumah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426924/
https://www.ncbi.nlm.nih.gov/pubmed/35981004
http://dx.doi.org/10.1371/journal.pgen.1010324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426924/
https://www.ncbi.nlm.nih.gov/pubmed/35981004
http://dx.doi.org/10.1371/journal.pgen.1010324

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