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Discovery of positive and purifying selection in metagenomic time series of hypermutator microbial populations
A general method to infer both positive and purifying selection during the real-time evolution of hypermutator pathogens would be broadly useful. To this end, we introduce a Simple Test to Infer Mode of Selection (STIMS) from metagenomic time series of evolving microbial populations. We test STIMS o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9426924/ https://www.ncbi.nlm.nih.gov/pubmed/35981004 http://dx.doi.org/10.1371/journal.pgen.1010324 |