New pyrazolylpyrazoline derivatives as dual acting antimalarial-antileishamanial agents: synthesis, biological evaluation and molecular modelling simulations

Promising inhibitory activities of the parasite multiplication were obtained upon evaluation of in vivo antimalarial activities of new pyrazolylpyrazoline derivatives against Plasmodium berghei infected mice. Further evaluation of 5b and 6a against chloroquine-resistant strain (RKL9) of P. falciparu...

Descripción completa

Detalles Bibliográficos
Autores principales: Bekhit, Adnan A., Lodebo, Eskedar T., Hymete, Ariaya, Ragab, Hanan M., Bekhit, Salma A., Amagase, Kikuko, Batubara, Afnan, Abourehab, Mohammed A. S., Bekhit, Alaa El-Din A., Ibrahim, Tamer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427035/
https://www.ncbi.nlm.nih.gov/pubmed/36036155
http://dx.doi.org/10.1080/14756366.2022.2117316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427035/
https://www.ncbi.nlm.nih.gov/pubmed/36036155
http://dx.doi.org/10.1080/14756366.2022.2117316

Ejemplares similares