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Non-canonical function of an Hif-1α splice variant contributes to the sustained flight of locusts

The hypoxia inducible factor (Hif) pathway is functionally conserved across metazoans in modulating cellular adaptations to hypoxia. However, the functions of this pathway under aerobic physiological conditions are rarely investigated. Here, we show that Hif-1α2, a locust Hif-1α isoform, does not in...

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Detalles Bibliográficos
Autores principales: Ding, Ding, Zhang, Jie, Du, Baozhen, Wang, Xuanzhao, Hou, Li, Guo, Siyuan, Chen, Bing, Kang, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427102/
https://www.ncbi.nlm.nih.gov/pubmed/36039636
http://dx.doi.org/10.7554/eLife.74554