Artificially stimulating retrotransposon activity increases mortality and accelerates a subset of aging phenotypes in Drosophila

Transposable elements (TEs) are mobile sequences of DNA that can become transcriptionally active as an animal ages. Whether TE activity is simply a by-product of heterochromatin breakdown or can contribute toward the aging process is not known. Here, we place the TE gypsy under the control of the UA...

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Detalles Bibliográficos
Autores principales: Rigal, Joyce, Martin Anduaga, Ane, Bitman, Elena, Rivellese, Emma, Kadener, Sebastian, Marr, Michael T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427105/
https://www.ncbi.nlm.nih.gov/pubmed/35980024
http://dx.doi.org/10.7554/eLife.80169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427105/
https://www.ncbi.nlm.nih.gov/pubmed/35980024
http://dx.doi.org/10.7554/eLife.80169

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