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Artificially stimulating retrotransposon activity increases mortality and accelerates a subset of aging phenotypes in Drosophila
Transposable elements (TEs) are mobile sequences of DNA that can become transcriptionally active as an animal ages. Whether TE activity is simply a by-product of heterochromatin breakdown or can contribute toward the aging process is not known. Here, we place the TE gypsy under the control of the UA...
Autores principales: | Rigal, Joyce, Martin Anduaga, Ane, Bitman, Elena, Rivellese, Emma, Kadener, Sebastian, Marr, Michael T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427105/ https://www.ncbi.nlm.nih.gov/pubmed/35980024 http://dx.doi.org/10.7554/eLife.80169 |
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