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Nuclear fascin regulates cancer cell survival

Fascin is an important regulator of F-actin bundling leading to enhanced filopodia assembly. Fascin is also overexpressed in most solid tumours where it supports invasion through control of F-actin structures at the periphery and nuclear envelope. Recently, fascin has been identified in the nucleus...

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Detalles Bibliográficos
Autores principales: Lawson, Campbell D, Peel, Samantha, Jayo, Asier, Corrigan, Adam, Iyer, Preeti, Baxter Dalrymple, Mabel, Marsh, Richard J, Cox, Susan, Van Audenhove, Isabel, Gettemans, Jan, Parsons, Maddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427113/
https://www.ncbi.nlm.nih.gov/pubmed/36039640
http://dx.doi.org/10.7554/eLife.79283