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Randomized Trial of Metformin With Anti-Tuberculosis Drugs for Early Sputum Conversion in Adults With Pulmonary Tuberculosis

BACKGROUND: Metformin, by reducing intracellular Mycobacterium tuberculosis growth, can be considered an adjunctive therapy to anti-tuberculosis treatment (ATT). We determined whether metformin with standard ATT reduces time to sputum culture conversion and tissue inflammation in adults with pulmona...

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Detalles Bibliográficos
Autores principales: Padmapriydarsini, Chandrasekaran, Mamulwar, Megha, Mohan, Anant, Shanmugam, Prema, Gomathy, N S, Mane, Aarti, Singh, Urvashi B, Pavankumar, Nathella, Kadam, Abhijeet, Kumar, Hemanth, Suresh, Chandra, Reddy, Devaraju, Devi, Poornaganga, Ramesh, P M, Sekar, Lakshmanan, Jawahar, Shaheed, Shandil, R K, Singh, Manjula, Menon, Jaykumar, Guleria, Randeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427151/
https://www.ncbi.nlm.nih.gov/pubmed/34849651
http://dx.doi.org/10.1093/cid/ciab964