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Differential expression on mitochondrial tryparedoxin peroxidase (mTcTXNPx) in Trypanosoma cruzi after ferrocenyl diamine hydrochlorides treatments

Resistance to benznidazole in certain strains of Trypanosoma cruzi may be caused by the increased production of enzymes that act on the oxidative metabolism, such as mitochondrial tryparedoxin peroxidase which catalyses the reduction of peroxides. This work presents cytotoxicity assays performed wit...

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Detalles Bibliográficos
Autores principales: Kohatsu, Andréa A.N., Silva, Flávia A.J., Francisco, Acácio I., Rimoldi, Aline, Silva, Marco T.A., Vargas, Maria D., Rosa, João A. da, Cicarelli, Regina M.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427605/
https://www.ncbi.nlm.nih.gov/pubmed/27918890
http://dx.doi.org/10.1016/j.bjid.2016.10.010