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Effects of splenectomy on skin inflammation and psoriasis-like phenotype of imiquimod-treated mice
Imiquimod (IMQ) is widely used as animal model of psoriasis, a chronic inflammatory skin disorder. Although topical application of IMQ to back skin causes splenomegaly in mice, how the spleen affects the psoriasis-like phenotype of IMQ-treated mice remains unclear. In this study, we analyzed the cel...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427736/ https://www.ncbi.nlm.nih.gov/pubmed/36042262 http://dx.doi.org/10.1038/s41598-022-18900-7 |