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Effects of splenectomy on skin inflammation and psoriasis-like phenotype of imiquimod-treated mice

Imiquimod (IMQ) is widely used as animal model of psoriasis, a chronic inflammatory skin disorder. Although topical application of IMQ to back skin causes splenomegaly in mice, how the spleen affects the psoriasis-like phenotype of IMQ-treated mice remains unclear. In this study, we analyzed the cel...

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Detalles Bibliográficos
Autores principales:	Shinno-Hashimoto, Hiroyo, Eguchi, Akifumi, Sakamoto, Akemi, Wan, Xiayun, Hashimoto, Yaeko, Fujita, Yuko, Mori, Chisato, Hatano, Masahiko, Matsue, Hiroyuki, Hashimoto, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427736/ https://www.ncbi.nlm.nih.gov/pubmed/36042262 http://dx.doi.org/10.1038/s41598-022-18900-7

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