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TTYH family members form tetrameric complexes at the cell membrane

The conserved Tweety homolog (TTYH) family consists of three paralogs in vertebrates, displaying a ubiquitous expression pattern. Although considered as ion channels for almost two decades, recent structural and functional analyses refuted this role. Intriguingly, while all paralogs shared a dimeric...

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Detalles Bibliográficos
Autores principales: Melvin, Emelia, Kalaninová, Zuzana, Shlush, Elia, Man, Petr, Giladi, Moshe, Haitin, Yoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427776/
https://www.ncbi.nlm.nih.gov/pubmed/36042377
http://dx.doi.org/10.1038/s42003-022-03862-3